NPC Research Hotels
Join the expertsThe NPC offers the newest proteomics technologies and facilities in specialised Research Hotels for joint projects with external scientists. You can address your subject of interest in collaboration with experienced personnel in our Hotels.
Please see the section below to get a first impression of our expertise and facilities. If you have any specific questions about our technologies you can directly contact the respective Hotel manager (see Hotel profiles). If you have more general questions about our Research Hotels and the conditions for joint projects, you are welcome to contact the This e-mail address is being protected from spambots. You need JavaScript enabled to view it . Proposals for joint projects should always be set-up in cooperation with the respective Research Hotel manager. Selection of proposals and applicants will be based on scientific quality and fit into the NPC.
For further information please see NPC Research Hotel general guidelines
Please use the respective NPC formats for project planning , project reports and training reports.
Research Hotels
Analytical Hotel Utrecht (Utrecht University)In the hotel, innovative mass spectrometic methods are developed and implemented for the efficient and detailed characterization of biomolecules in their relation to their biological function. The scientific focus ranges from single protein identifications to the analysis of complex, whole cell lysate, samples and determination of posttranslational modifications.
Analytical Hotel Rotterdam (Erasmus MC)
The hotel develops mass spectrometry based proteomics methodologies and protein separation techniques for the qualitative and quantitative analysis of (sub)proteomes, and provides mass spectrometry and proteomics services for the local scientific community as well for external research.
Analytical Hotel Groningen (University of Groningen)
Expertise and assistance in experiments requiring the purification, separation and high resolution analysis of proteins employing proteomics tools, as well as biochemical and biophysical techniques. These include mebrane and organelle isolation, ultracentrifugation (analytical and preparative), gel- and solution (chromatography)-based separation of proteins and peptides (1- and 2- dimensional) coupled to a mass spectrometry (MS).
Analytical Hotel Wageningen (Plant Research International/Wageningen University)
Plant development and signal transduction in plant meristems. Proteomics technologies will be used in the hotel to perform protein profiling for comparitive proteomics and to unravel signaling pathways and the involved protein complexes.
Analytical Hotel Delft (Delft University of Technology)
Up to date peptidomics in all of its aspects: both qualitative and quantitative analysis of the subset of the proteome designated as the peptidome: naturally occurring (native, endogenous) peptides with important biological (regulatory, signal, (neuro) hormonal) functions. Focus will be on various peptide chemical identification strategies, including de novo sequencing, peptide bioinformatics, the study of bioactive peptide location, as well as their(physiological/pharmacological) activities.
Bioinformatics Hotel Utrecht (Utrecht University)
Development of bioinformatics software and algorithms that facilitate proteomics research: (raw) data (pre) processing, data storage and dissemination, knowledge extraction.
Cell Culture Hotel Utrecht (UMCU)
The scientific focus of the Cell Culture hotel is to provide key technologies for targeted proteomic analyses of embryonic stem cells (ESCs), induced pluripotent stem cells (iPS) and differentiated cells. This includes selective tagging of proteins using bacterial artificial chromosomes (BACs) and viral-mediated gene manipulation. We offer a variety of different epitopes for efficient tagging and purification of target proteins expressed at endogenous levels. This enables isolation of protein complexes for proteomic and genomic analyses.
Cell Sorting Hotel (Utrecht University)
Many protein complexes differ between cell types. The Cell Sorting Hotel Utrecht (CSHU) offers equipment and expertise to isolate specific cell types from plant tissues. The goal is to extract proteins from sorted cells and subject them to proteomic analysis. Cell-specific proteomics is a technical goal in itself and as soonas this procedure has been optimized for Arabidopsis all plant NPCII groups will have access to the facility using Arabidopsis, tomato and potato cells.